Urinary collagen degradation products as early markers of progressive renal fibrosis.

J Transl Med · 2017 · PMC5358042 · PMID 28320405

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borderline significanceno p-value reported

In addition, uC1M at 6 weeks associated borderline significance with the PAS-score at 12 weeks in untreated ADR-rats.

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a decreasing trendno p-value reported

Right panels) showed a decreasing trend in pC3M over time, while FTY720-treated ADR-rats showed a significant decrease at 12 weeks compared to baseline (P < 0.01) and 6 weeks (Fig. 1 b; P < 0.001). uC3M levels in the FTY720-treated ADR-rats (Fig. 1 d) increased significantly over time at both 6 weeks (P < 0.01) and 12 weeks (P < 0.001) compared to baseline values. uC1M levels in healthy controls treated with FTY720 showed a significant decrease over time at 6 (P < 0.05) and 12 weeks (P < 0.001).

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