tendency toward significancep = 0.059
In the depleted groups of Wistar rats, 5-HT levels were reduced in the PFC ( F 1,23 = 20.86; p < 0.001) and hippocampus ( F 1,24 = 5.89; p < 0.023) (see Table 2 ), and there was a tendency toward significance in the amygdala ( F 1,24 = 3.92; p = 0.059). 5-HIAA levels were decreased in the PFC ( F 1,23 = 29.52; p < 0.001), striatum ( F 1,22 = 4.79; p = 0.040), amygdala ( F 1,24 = 29.79; p < 0.001) and hippocampus ( F 1,24 = 19.837; p < 0.001).