Yet, there was no correlation between PIGD severity and 5-HT level in CSF, which might be explained that patients in our study were at relatively early stage and the role of 5-HT dysfunction played on cognition in PIGD patients might not be significant.
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Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters.
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