Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis.

Acta Neuropathol Commun · 2017 · PMC5363023 · PMID 28330496

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possibly significantno p-value reported

The relationship between Ca 2+ dysregulation and other pathogenic mechanisms in IBM is complex, but possibly significant for disease progression.

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highly significantno p-value reported

This approach allowed for detection of subtle but still highly significant expression changes at the gene and pathway level.

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