The relationships between iron metabolism and FGF23 are further reflected by highly significant negative correlations between total serum iron concentrations and FGF23 in ADHR kindreds ( Imel et al., 2011 ), and in anemic patients treated with specific iron preparations ( Shimizu et al., 2009 , Wolf et al., 2013 , Schouten et al., 2009a , Schouten et al., 2009b ).
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The metabolic bone disease associated with the <i>Hyp</i> mutation is independent of osteoblastic HIF1α expression.
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