Highly significant association, from the meta-analysis of three GWAS, of the TREM2 variant R47H with AD was found and then validated by sequencing an additional 1,887 AD patients and 4,061 controls [ 82 ].
← all excerpts
Recent Progress in Alzheimer's Disease Research, Part 2: Genetics and Epidemiology.
2
—
—
The sentences
Other studies have shown a decline in the acceleration rate of incidence despite it maintaining an increasing trend with extremely old age [ 16, 17 ].