Single pemetrexed is noninferior to platinum-based pemetrexed doublet as first-line treatment on elderly Chinese patients with advanced nonsquamous nonsmall cell lung cancer.

The difference in the DCR did not achieve significance among the 3 groups ( P > 0.05). χ 2 test (Table 2 ) revealed that DCR after 2 pemetrexed-based treatment cycles was significantly associated with smoking status (current or previous history of smoking cigarettes), PS score, TNM stage, and TS expression levels.

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