Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia.

Physiol Rep · 2017 · PMC5371564 · PMID 28320892

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0.0650

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0.0650

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an increasing trendP = 0.065so close (0.05 < p ≤ 0.1)

The contraction of the aortic rings in response to high KCl from the older Spr −/− mice (2.57 ± 0.41 mN) showed an increasing trend compared with that in the wild‐type mice of the same age (1.69 ± 0.17 mN) ( P = 0.065, n = 10, Student's t ‐test).

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