Glutamine-Glutamate Cycle Flux Is Similar in Cultured Astrocytes and Brain and Both Glutamate Production and Oxidation Are Mainly Catalyzed by Aspartate Aminotransferase.

Biology (Basel) · 2017 · PMC5372010 · PMID 28245547

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highly significantno p-value reported

However, the remaining glutamate oxidation supports a highly significant role of AAT, even in the presence of the relatively high glutamate concentration in the medium which might have caused a similar inhibition as in cultures with normal GDH function.

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