Interestingly, previous clinical studies conducted by our group show highly significant correlation of urinary THaldo excretion with that of cortisol metabolites [ 44 ].
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ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure.
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Plasma cortisol levels did not change significantly between the different genotypes, but there was an apparent trend towards a raised cortisol:ACTH ratio in the T group [ 27 ].