The Essential Role of Pin1 via NF-κB Signaling in Vascular Inflammation and Atherosclerosis in ApoE^-/- Mice.

Compared with oxLDL stimulation, pretreatment with NF-κB inhibitor BAY11-7082 resulted in a highly significant reduction in oxLDL-induced upregulation of VCAM-1 and attenuated THP-1 cell adhesion to oxLDL-stimulated EA.hy926 cells ( Figure 4 E–H).

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