SNP rs2030136 is located within the third intron of the SKAP2 gene (src kinase associated phosphoprotein 2; 7p15.2) and showed highly significant association in the combined analysis ( P combined = 3.39 × 10 −7 ) ( Fig. 2c ).
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Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci.
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