Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism.

Brain · 2017 · PMC5379862 · PMID 27807026

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highly significantno p-value reported

However, p-Ser65-Ub signals remained reduced and highly significant over longer times of valinomycin treatment only in p.G411S heterozygotes.

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