RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response.

Leukemia · 2017 · PMC5380219 · PMID 27909306

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borderline significantno p-value reported

However, no mutations were found in these genes, low MTF2 expression does not affect PFS or OS, and the association between low TMED5 expression and shorter survival is only borderline significant. 11 , 12 To uncover potentially clinically relevant tumor suppressors on 1p22, we performed an in-depth genetic analysis of 1p22 in MM.

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