of borderline significanceP =0.06
Presence of abnormal karyotype was significant in univariate analysis for MFFS ( P =0.008, HR 6.3; 95% CI 1.62–24.84) and was of borderline significance during multivariable analysis ( P =0.06); a similar trend of significance was noted between abnormal karyotype and LFS ( P =0.05; data not shown).