marginally significantP = 0.09
We compared the locomotor response to morphine of these two groups, and marginally significant difference was found [main effects of group (successful/ failed): F 1, 45 = 3.01, P = 0.09; time: F 13, 585 = 11.17, P <0.001; interaction: F 13, 585 = 3.54, P <0.001; Fig 2A ].