Sickle cell trait is associated with controlled levels of haem and mild proinflammatory response during acute malaria infection.

Clin Exp Immunol · 2017 · PMC5383446 · PMID 28142190

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borderline significanceno p-value reported

Levels of IL‐13 also increased significantly during malaria infection in both genotypical groups (HbAS, P = 0·030 and HbAA, P = 0·050); however, the increase was at borderline significance in the HbAA group.

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