A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension.

BMC Pulm Med · 2017 · PMC5383973 · PMID 28388887

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp = 6.0 × 10 −8actually significant

Despite the small sample size, the burden of association between BMPR2 and PAH was highly significant ( p = 6.0 × 10 −8 ) compared to the genome-wide significance threshold ( p < 2.4 × 10 −6 ) after Bonferroni correction for approximately 21,000 genes (Fig. 2 ).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.