Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells.

Sci Rep · 2015 · PMC5390089 · PMID 25735798

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0.0010

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantp < 0.001actually significant

Note that this effect was highly significant ( p < 0.001) in THP-1 cells.

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markedly significantp < 0.05actually significant

Both cell types showed a markedly significant decrease ( p < 0.05) in the basal OCR after a 24 h combination treatment compared with the untreated control, and not surprisingly, we also observed a significant decrease ( p < 0.05) in the ECAR (extracellular acidic ratio; an indicator of glycolysis flux) following a combination treatment in both cell types ( supporting information, Figure S9 ).

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