GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.

Hum Mol Genet · 2017 · PMC5390679 · PMID 28199695

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modestly significantno p-value reported

While the remaining pairwise tests all failed to demonstrate a significant slope or intercept when not constrained through the origin, each did exhibit at least a modestly significant positive slope when constrained through the origin, suggesting some degree of pleiotropy or causality between each trait ( Fig. 4 ).

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