MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis.

ERJ Open Res · 2017 · PMC5395293 · PMID 28435843

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a slight trendno p-value reported

We thus assume that differential OPN proteolysis, affecting assay sensitivity and variability, might account for the observed lack of statistical significance at baseline and 4 months, although a slight trend to higher OPN levels in patients with IPF was indeed visible at 4 months.

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