Short-term exposure to PM_2.5 and vanadium and changes in asthma gene DNA methylation and lung function decrements among urban children.

Therefore, analysis for mediation by methylation of V on lung function was deferred. Sensitivity analyses First, after controlling for time spent home, the main findings in Table 2 remained similar although the association between V and methylation of IL4 CpG −326 became borderline significant (RR [95% CI]: 0.81 [0.66-1.00]; p = 0.052 for IL4 CpG −326 and 0.81 [0.67-0.97]; p = 0.026 for IFNγ CpG −54 ).

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