Subtle, yet consistent, differences between the form II and form III Rubisco structures may be significant: variation in the lengths and conformations of the loops that connect secondary structure elements are evident in both sequence and structural alignments (regions i–viii in supplemental Figs.
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A unique structural domain in <i>Methanococcoides burtonii</i> ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) acts as a small subunit mimic.
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