There is a highly significant failure to repress the early factor Chinmo and activate the late factors Broad and E93 in the absence of ecdysone signaling within type I central brain neuroblasts. 6) The requirement of ecdysone/EcR in the transition of the neuroblasts is not absolute since the transition still occurs in their absence, although very delayed (120-160h).
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Steroid hormone induction of temporal gene expression in <i>Drosophila</i> brain neuroblasts generates neuronal and glial diversity.
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