Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.

In detail, a highly significant decrease of collagen IV- and Iba-staining was found at the ischemic border zone with respect to the ischemic core (p < 0.001 for both markers; Wilcoxon test), while the signals were further reduced in the contralateral striatum (p < 0.001 for both markers; Wilcoxon test).

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