Barely Significant
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Core Genes Evolve Rapidly in the Long-Term Evolution Experiment with Escherichia coli.

Genome Biol Evol · 2017 · PMC5406848 · PMID 28379360

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highly significantno p-value reported
In genomes from the nonmutator populations, we observe a highly significant excess of nonsynonymous mutations in the core genes.

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