Allogeneic pASC transplantation in humanized pigs attenuates cardiac remodeling post-myocardial infarction.

Interestingly, pigs that received 1 million and 2 million cell/Kg showed a slight trend toward non-perfused area reduction ( Fig 3A and 3B ).

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This finding may be significant, and we speculated that the reduction in the scar area in the highest dosage cell group is a consequence of combining a more elastic (less stiff) scar with an increased perfusion in the adjacent tissue, providing increased mechanical performance to the ventricle.

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