Despite the Australian study of FFP in snakebite showing a highly significant improvement in coagulopathy, it did not lead to earlier discharge or clinical benefit 5 .
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A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming.
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The sentences
This reduced the effective power of the study, and is one potential reason for the negative intention to treat outcome, despite a favorable trend in patients actually given FFP.