borderline significantp = 0.05
When two groups were defined a posteriori based on the insulin values of LDIGIT (120–150 min) , there was a borderline significant group by time interaction for PAI-1 ( p = 0.05; n = 49) and the change in PAI-1 was greater in the insulin-resistant group (177, 61 for HMD vs. 128, 52 ng/mL for HWD; p < 0.001) than in the insulin-sensitive group (137, 80 for HMD vs. 113, 39 ng/mL for HWD; p = 0.02).