[ 48 ] observed, in a cohort of 278 patients from the GeparTrio trial, a highly significant correlation and a high overall agreement between IHC, supplemented by SISH for equivocal cases, and qRT-PCR in determining HER2 status.
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Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases.
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