We found that RTX given intraluminally one week before toxin A resulted in highly significant inhibition of toxin A-induced luminal fluid accumulation ( Figure 3(a) ), colonic MPO concentration ( Figure 3(b) ), and strong protection against toxin A-induced structural damage to the colon ( Figure 4 ).
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Intraluminal Administration of Resiniferatoxin Protects against <i>Clostridium difficile</i> Toxin A-Induced Colitis.
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