AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy.

J Exp Med · 2017 · PMC5413341 · PMID 28416651

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did not quite reach statistical significanceno p-value reported

Because of high variability, the effect did not quite reach statistical significance for SC3 scFv–treated mice in either region ( Fig. 3, C and D ).

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a nonsignificant trendno p-value reported

Treatment with either SC1 or SC3 scFv revealed a nonsignificant trend toward lowering the levels of p-tau in assessing the entire hippocampus ( Fig. 3, A and B ).

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