Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients.

Nevertheless, the aforementioned studies in septic patients have shown that gene expression of HLA-DRA correlates well with flow cytometric analysis of mHLA-DR, with correlation coefficients ranging from 0.74 to 0.84 [ 27 – 29 ]; however, in one of these, a more moderate but still highly significant correlation coefficient of 0.53 was found [ 39 ].

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