Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models.

Mol Ther Nucleic Acids · 2017 · PMC5415970 · PMID 28624196

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

failed to reach significancep = 0.09so close (0.05 < p ≤ 0.1)

HMW ATXN3 trended toward a decrease in ASO-4-treated mice, but failed to reach significance due to variability across mice (p = 0.09).

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