Validation of Nomograms for Survival and Metastases after Hysterectomy and Adjuvant Therapy in Uterine Cervical Cancer with Risk Factors.

In another surgical study, the increase of age decreased the DFS, with a hazard ratio of 0.935 with marginal significance ( P = 0.052) [ 17 ], and, in a Japanese study using CCRT in huge FIGO IB–IIB cervical cancers, age less than 48 was an independent poor prognosis factor [ 18 ].

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Multiple lymph node metastases ( P = 0.006, 0 versus ≥3) were significantly associated with DFS, and large tumor size ( P = 0.058), young age ( P = 0.074, ≤40 versus 41–64), and high serum SCC ( P = 0.093) were borderline significant ( Table 2 ).

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