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Long-term safety of once-daily, dual-release hydrocortisone in patients with adrenal insufficiency: a phase 3b, open-label, extension study.

Eur J Endocrinol · 2017 · PMC5425941 · PMID 28292927

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an overall trendno p-value reported
In addition, there was an overall trend for dose reduction in patients receiving the highest daily doses at baseline (35 and 40 mg) so that dose levels were more in line with clinical practice in the rest of Europe.

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