Barely Significant
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CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.

Nat Commun · 2017 · PMC5431906 · PMID 28232751

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highly significantp < 0.05actually significant
We performed immunoprecipitation-mass spectrometry (IP-MS) identification of N-terminal-tagged CLK2-associated proteins (4 FLAG-tagged replicates, one untagged CLK2), using tandem mass tags (TMT) mass spectrometry and observed highly significant enrichment (Fig. 6a , Supplementary Data 32 ) of both known CLK-interacting proteins (28/97 known, B-H adjusted Wald p < 0.05) including CLK1 and additional splicing factors (98/270 total enriched, B-H adjusted Wald p < 0.05).

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