Impaired Spinal Glucocorticoid Receptor Signaling Contributes to the Attenuating Effect of Depression on Mechanical Allodynia and Thermal Hyperalgesia in Rats with Neuropathic Pain.

Front Cell Neurosci · 2017 · PMC5437111 · PMID 28579944

Europe PMC DOI

hedged sentence

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

an increasing trendp = 0.095so close (0.05 < p ≤ 0.1)

In the vehicle groups, there was an increasing trend in BDNF expression ( p = 0.095) and a significant up-regulation of TrkB expression in NOB-SNL rats ( p < 0.001) compared with NOB-Sham rats, while the expression of BDNF and TrkB in OB-SNL rats was lower than that in NOB-SNL rats ( p = 0.002 and p < 0.001, respectively) and OB-Sham group ( p < 0.001).

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