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Ipilimumab as a Cause of Severe Pan-Colitis and Colonic Perforation.

Cureus · 2017 · PMC5438238 · PMID 28533998

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a decreasing trendno p-value reported
Due to concern for acute gastrointestinal (GI) bleed and a decreasing trend in the patients Hgb, the patient was started on intravenous pantoprazole and underwent a colonoscopy and esophagogastroduodenoscopy (EGD) to rule out a brisk upper GI bleed.

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