We have observed that coblockade of the putative coinhibitor CD160 did not enhance T cell responses, which could be explained by a minor significance of CD160 inhibition in this setting, but also by reduced costimulation via HVEM under conditions where two of its ligands are blocked.
← all excerpts
PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.
1
—
—