a nonsignificant trendP = 0.0678
In the HR cohort, patients treated with Gla-300 showed a nonsignificant trend toward lower nocturnal hypoglycemia compared with those treated with Gla-100 (EDITION 2, 25.3% vs. 38.0%, P = 0.0678; EDITION 3, 24.2% vs. 32.7%, P = 0.1903) ( Table 3 ).