While this follows an increasing trend of nanosized bubble formulations being reported in literature [ 16 , 25 – 31 ], a key concern regarding bubbles of this nature has been their echogenic stability, it being anticipated that gas will not be effectively retained within nanosized particles [ 32 ].
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Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina.
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