7c ). Inhibition of autophagy by CQ caused a highly significant increase in etoposide- as well as doxorubicin-induced apoptosis and caspase-3/7 activity in SH-EP/shCtr as well as in NB15/shCtr cells (Fig. 7d and e ).
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C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy.
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