KMT2D , on the other hand, is part of the COMPASS-like complex (COMplex of Proteins ASsociated with Set1) responsible for mono-methylation of H3K4, and is recruited by, e.g., nuclear binding receptors such as the estrogen receptor and by other transcription factors such as p53, which may be significant for OCCC tumorigenesis ( 63 ).
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Involvement of Chromatin Remodeling Genes and the Rho GTPases <i>RhoB</i> and <i>CDC42</i> in Ovarian Clear Cell Carcinoma.
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