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Protective effect of chlorogenic acid on the focal cerebral ischemia reperfusion rat models.

Saudi Pharm J · 2017 · PMC5447441 · PMID 28579891

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an increasing trendP > 0.05actually significant
3.4 Effect on the EPO and HIF-1α levels of focal cerebral ischemia reperfusion rat models From the data in Table 5 , compared with the model group, the EPO level in brain tissue of rats in the Nimodipine group and medium and high dosage of chlorogenic acid groups significantly increased ( P < 0.01), and the EPO level in brain tissue of rats in the low dosage of chlorogenic acid group showed an increasing trend ( P > 0.05), and the HIF-1α level in brain tissue of rats in the Nimodipine group and medium and high dosage of chlorogenic acid groups significantly increased ( P < 0.01), and the HIF-1α level in brain tissue of rats in the low dosage of chlorogenic acid group obviously increased ( P < 0.05), sugg

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