Limited Utility of Polymerase Chain Reaction in Induced Sputum Specimens for Determining the Causes of Childhood Pneumonia in Resource-Poor Settings: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study.

Among high-quality IS specimens, there were no statistically significant differences in organism density in the IS specimens from cases with radiographic pneumonia compared with nonpneumonia cases, with the exception of a marginally significant difference for cytomegalovirus (median Ct, 27.9 vs 28.5; P = .01) ( Figure 2 ).

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