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The safety and tolerability of inhaled treprostinil in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

Pulm Circ · 2017 · PMC5448530 · PMID 28680567

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a positive trendno p-value reported
A positive trend was seen in 6MWT as the majority of patients either maintained or improved, while two patients had worsening.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.