Phase II Study of Adjuvant Immunotherapy with the CSF-470 Vaccine Plus Bacillus Calmette-Guerin Plus Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor vs Medium-Dose Interferon Alpha 2B in Stages IIB, IIC, and III Cutaneous Melanoma Patients: A Single Institution, Randomized Study.

Front Immunol · 2017 · PMC5449770 · PMID 28620382

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp = 0.0001actually significant

In the vaccine arm, the IFN-γ secreting T cells increased in 14/15 pts and in case of pt #013 they were already high in the PRE sample and remained unchanged in the POST1 sample The difference between IFN-γ secreting T cells in PRE and POST1 samples was statistically highly significant ( p = 0.0001).

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