Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

Dis Model Mech · 2017 · PMC5451164 · PMID 28100513

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

of borderline significanceP =0.057so close (0.05 < p ≤ 0.1)

We found that there was a decline, which was of borderline significance, in axon diameters of sciatic nerves of SLICK-H::Ranbp2 flox/flox compared with SLICK-H::Ranbp2 +/+ mice ( P =0.057), whereas there were no significant differences in axon diameters of phrenic nerves between genotypes ( P =0.10).

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