Barely Significant
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The increasing prevalence of HIV/<i>Helicobacter pylori</i> co-infection over time, along with the evolution of antiretroviral therapy (ART).

PeerJ · 2017 · PMC5452935 · PMID 28584718

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a decreasing trendno p-value reported
pylori infection has had a decreasing trend, most probably by effective application of H. pylori eradication therapy ( Malfertheiner et al., 2012 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.